This expansion to Pandemic includes new event cards, new role cards, rules for 5 players, and optional game challenges to increase the difficulty, such as the 'Legendary' difficulty level, the Virulent Strain challenge, the Mutation challenge, and the Bio-Terrorist challenge. These challenges can be mixed together to make the game even harder. (Also includes a petri dishes to store your diseases and pawns.)
- Virulent Strain challenge: makes one disease become particularly deadly in unpredictable ways.
- Mutation Challenge: adds a fifth (purple) disease that behaves differently than the original four.
- Bio-Terrorist Challenge: pits one player against the others!
*NOTE* This is not the full game, Pandemic is required for play.